Sample Reports

The easiest way to show what we can do is through example.

The following study is especially interesting in that the researchers make their point by producing a negative outcome with minimal data and then extrapolate this to a controversial and speculative conclusion. This is quite different from the typical clinical trial where minimal treatment effects are highlighted and emphasized to attain FDA approval. Typically, a negative outcome is not reported because of commercial research funding for the approval process.

This study, often refered to as the Klempner study, was published with much publicity in a prestigious journal, The New England Journal of Medicine in 2001 and is routinely cited as evidence that "long-term antibiotics" are not effective in treating Lyme disease. On cursory examination the study appears valid, but closer analysis shows that few results were presented and then repeatedly made less sensitive.

Verim Research Sample AnalysisTwo controlled trials of antibiotic treatment in patients with persistent symptoms and a history of Lyme disease, New England Journal of Medicine, 2001. 345(2):85-92. Klempner, M. S., Hu, L. T., Evans, J., Schmid, C. H., Johnson, G. M., Trevino, R. P., Norton, D., Levy, L., Wall, D., McCall, J., Kosinski, M., Weinstein, A. [PDF]